Protective Effects of Viscoelastic Substances on air Bubble Damage During Phacoemulsification
Journal of the Korean Ophthalmological Society
;
: 2273-2279, 2002.
Artículo
en Coreano
| WPRIM
| ID: wpr-20612
ABSTRACT
PURPOSE:
To determine whether viscoelastic materials are effective to protect the corneal endothelium from air bubble damage.METHODS:
Human eye bank (n=12) and rabbit (n=22) eyes underwent a standardized phacoemulsification procedure with or without viscoelastic material [1% sodium hyaluronate (Healon(R)), 1.4% sodium hyaluronate (Healon GV(R)), 3% sodium hyaluronate with 4% chondroitin sulfate (Viscoat(R))]. The integrity of the endothelium was examined after the procedure with F-actin staining and scanning electron microscopy (SEM).RESULTS:
In the phacoemulsification experiment without viscoelastic material, with Healon, and with Healon GV, the endothelium of both human and rabbit corneas had many areas of cell loss in a pattern consistent with air bubble damage. But with Viscoat, endothelial cells remained intact.CONCLUSIONS:
We found that Viscoat was effective to protect the endothelium from air bubble damage. Viscoat seems to protect the endothelium by acting as a physical barrier.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Endotelio Corneal
/
Microscopía Electrónica de Rastreo
/
Sulfatos de Condroitina
/
Actinas
/
Facoemulsificación
/
Córnea
/
Células Endoteliales
/
Endotelio
/
Bancos de Ojos
/
Sustancias Viscoelásticas
Límite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Año:
2002
Tipo del documento:
Artículo
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