Cellular Plexiform Fibrohistiocytic Tumor / 대한피부과학회지
Korean Journal of Dermatology
;
: 396-399, 2015.
Artículo
en Coreano
| WPRIM
| ID: wpr-206791
ABSTRACT
Plexiform fibrohistiocytic tumor (PFHT) is a rare mesenchymal neoplasm of intermediate malignancy and possibly of myofibroblast origin. It is morphologically divided into 3 groups cellular, fibrous, and mixed. A 4-year-old girl presented with an irregular shaped subcutaneous mass on her left popliteal fossa for 6 months. The biopsy specimen showed multinodular tumor islands extending from dermis to subcutaneous layer, composed of histiocytes and osteoclast-like multinucleated giant cells, and circumscribed by fibrous tissue. Immunohistochemical staining was positive for CD68 in giant cells and histiocyte-like cells within tumor islands and faintly positive for smooth muscle actin around nodules. A cellular variant of PFHT was eventually diagnosed. Although PFHT comprises morphologically normal cells, it has the biological potential for malignant change and distal metastasis. Therefore, PFHT is categorized as a neoplasm of intermediate malignancy, and wide total excision with close follow-up is crucial.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Biopsia
/
Células Gigantes
/
Actinas
/
Dermis
/
Miofibroblastos
/
Islas
/
Histiocitos
/
Músculo Liso
/
Metástasis de la Neoplasia
Límite:
Child, preschool
/
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Año:
2015
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS