The Effect of Mometasone Furoate Cream on Skin Barrier Function in Patients with Allergic Contact Dermatitis / 대한피부과학회지
Korean Journal of Dermatology
;
: 347-350, 2015.
Artículo
en Coreano
| WPRIM
| ID: wpr-206800
ABSTRACT
BACKGROUND:
It is unclear how the usage of topical steroid agents affects skin barrier function.OBJECTIVE:
In order to follow up on previous research into this topic, we sought to investigate the effects of a 3-week application of topical mometasone cream on the alteration of skin barrier function.METHODS:
Twenty-six patients who had been clinically diagnosed with allergic contact dermatitis were enrolled. Topical mometasone cream was applied to the skin lesions. Clinical symptoms, transepidermal water loss (TEWL), corneometer unit, and pH value were measured on the initial visit, 1 week after treatment, and 3 weeks after treatment, and their values were compared.RESULTS:
Clinical symptoms showed improvement after topical mometasone cream was applied (p0.05).CONCLUSION:
This study found that treatment with topical mometasone cream for 3 weeks has no effect on skin barrier function. We believe that this research will help determine the optimal duration and dosage of topical steroid agents used for treating allergic contact dermatitis.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Piel
/
Estudios de Seguimiento
/
Dermatitis Alérgica por Contacto
/
Dermatitis por Contacto
/
Furoato de Mometasona
/
Concentración de Iones de Hidrógeno
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Año:
2015
Tipo del documento:
Artículo
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