Antimicrobial susceptibility of Campylobacter fetus subsp. fetus isolated from blood and synovial fluid
Yonsei Medical Journal
;
: 314-319, 1994.
Artículo
en Inglés
| WPRIM
| ID: wpr-207918
ABSTRACT
Campylobacter fetus subsp. fetus is a rare human pathogen, but can cause serious extraintestinal infections. Effective antimicrobial agent is required for the therapy, but we have very limited knowledge on the susceptibility of the organism. In this study, the susceptibility of 25 isolates of the organism to 14 antimicrobial agents was tested by an agar dilution method. Antimicrobial agents with low MIC ranges, in micrograms/ml, were meropenem Y or = 0.25, dirithromycin or = 1, amikacin, ofloxacin, tetracycline and erythromycin < or = 2. The MIC range of cefepime was 0.5-8 micrograms/ml, but those of other beta-lactams were relatively high. All of the isolates were interpreted to be susceptible to cefepime, meropenem, amikacin, gentamicin, ofloxacin, tetracycline and dirithromycin. A significant proportion of the isolates were either intermediate or resistant to ampicillin, cephalothin, cefotaxime, aztreonam, loracarbef and erythromycin. In conclusion, the organism remains susceptible to aminoglycosides and tetracycline. Greater in vitro activity of meropenem, ofloxacin and dirithromycin require clinical evaluation.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Líquido Sinovial
/
Sangre
/
Campylobacter fetus
/
Pruebas de Sensibilidad Microbiana
/
Antibacterianos
Límite:
Humanos
Idioma:
Inglés
Revista:
Yonsei Medical Journal
Año:
1994
Tipo del documento:
Artículo
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