Low-Grade Adenosquamous Carcinoma of the Breast with Diverse Expression Patterns of Myoepithelial Cell Markers on Immunohistochemistry: A Case Study
Korean Journal of Pathology
;
: 229-233, 2014.
Artículo
en Inglés
| WPRIM
| ID: wpr-207969
ABSTRACT
This paper reports a case of low-grade adenosquamous carcinoma (LGASC) arising in a 69-year-old woman, who presented with a 1-cm palpable mass on her right breast. Core needle biopsy diagnosed the mass as a fibroadenoma. After six months, the mass increased in size, and the patient received subsequent mammotome excision. On microscopic examination, bland-looking small glands were infiltrating into the fibrotic stroma with lymphocytic infiltrates at the periphery. Hematoxylin and eosin staining revealed relatively easily detectable myoepithelial cells along the outside in each of the glandular structures with variable degrees of squamous metaplasia. Based on histologic features, the patient was diagnosed with LGASC. LGASC is a rare variant of metaplastic carcinoma, which is characterized by a favorable prognosis. Due to the bland cytology and presence of myoepithelial cells, LGASC can be misdiagnosed as benign lesion. Additionally, inconsistent expression of myoepithelial markers could aid the diagnosis of LGASC.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pronóstico
/
Mama
/
Inmunohistoquímica
/
Fibroadenoma
/
Carcinoma Adenoescamoso
/
Eosina Amarillenta-(YS)
/
Diagnóstico
/
Biopsia con Aguja Gruesa
/
Hematoxilina
/
Metaplasia
Tipo de estudio:
Estudio diagnóstico
/
Estudio pronóstico
Límite:
Anciano
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Korean Journal of Pathology
Año:
2014
Tipo del documento:
Artículo
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