Role of Innate Immunity in the Pathogenesis of Type 1 and Type 2 Diabetes
Journal of Korean Medical Science
;
: 1038-1041, 2014.
Artículo
en Inglés
| WPRIM
| ID: wpr-208230
ABSTRACT
The importance of innate immunity in host defense is becoming clear after discovery of innate immune receptors such as Toll-like receptor or Nod-like receptor. Innate immune system plays an important role in diverse pathological situations such as autoimmune diseases. Role of innate immunity in the pathogenesis of metabolic disorders such as type 2 diabetes, metabolic syndrome or atherosclerosis that has not been previously considered as inflammatory disorders, is also being appreciated. Here, the role of innate immunity in the development of type 1 diabetes, a classical organ-specific autoimmune disease, and type 2 diabetes will be discussed, focusing on the role of specific innate immune receptors involved in these disease processes.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Páncreas
/
Citocinas
/
Modelos Inmunológicos
/
Diabetes Mellitus Tipo 1
/
Diabetes Mellitus Tipo 2
/
Inflamasomas
/
Inmunidad Innata
Tipo de estudio:
Estudio de etiología
Límite:
Animales
/
Humanos
Idioma:
Inglés
Revista:
Journal of Korean Medical Science
Año:
2014
Tipo del documento:
Artículo
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