Mitomycin C in Trabeculectomy with Cataract Extraction

ABSTRACT

We evaluated the effectiveness of combined extracapsular cataract extraction(ECCE), posterior chamber intraocullar lens implantation(PCIOL) and trabeculectomy with mitomycin C in patients with coexisting cataract and glaucoma. The charts were reviewed and compared of all patients who underwent combined procedure implantation without mitomycin C(group I) or with mitomycin C(group II) between 1990 and 1994 at Siloam Eye Hospital. A total of 44 eyes were included 27 eyes in group I and 17 in group II. Intraocular pressure was controlled successfully in 66.6% of eyes in group I (mean IOP 15.9 +/- 6.6mmHg) and in 88.2% of eyes in group II (mean IOP 13.1 +/- 4.0mmHg). Fifteen of 27 eyes(55.6%) had a best corrected visual acuity of 20/40 or better in group I and thirteen of 17 eyes(76.5%) in group n at 6 months follow up. Complications included corneal haziness, posterior capsular opacity and encapsulated or flattened bleb in group I and shallow anterior chamber, hypotony, hyphema and bleb leakage in group II. The combined procedure with adjunctive mitomycin C appears to be a safe and effective in treating patients with coexisting cataract and glaucoma.