Development of multifocal nodular lesions of a liver mimicking hepatic metastasis, following resection of an insulinoma in a child / 소아과
Korean Journal of Pediatrics
;
: 69-72, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-212742
ABSTRACT
Insulinoma, which arises from insulin-producing pancreatic beta cells, is a rare tumor in children. Only 5%-10% of insulinomas are malignant and undergo metastasis. We report a case of an 11-year-old girl who experienced hypoglycemia-related seizures induced by an insulinoma; after resection of the primary tumor, she developed hepatic focal nodular hyperplasia (FNH). Laboratory test results indicated marked hypoglycemia with hyperinsulinemia. Abdominal ultrasonography (US) and computed tomography results were normal; however, magnetic resonance imaging (MRI) showed a solid mass in the pancreatic tail. Therefore, laparoscopic distal pancreatectomy was performed. Two months after the surgery, an abdominal MRI revealed multiple nodular lesions in the liver. An US-guided liver biopsy was then performed, and histological examination revealed FNH without necrosis or mitotic activity. The patient has been free of hypoglycemia for 2 years, and recent MRI studies showed a decrease in the size of FNH lesions, without any evidence of metastasis. Even though no metastatic lesions are noted on imaging, close observation and follow-up imaging studies are required in a child with insulinoma that has malignant potential on histopathologic findings.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pancreatectomía
/
Pediatría
/
Convulsiones
/
Biopsia
/
Imagen por Resonancia Magnética
/
Ultrasonografía
/
Hiperplasia Nodular Focal
/
Células Secretoras de Insulina
/
Hiperinsulinismo
/
Hipoglucemia
Tipo de estudio:
Estudio diagnóstico
Límite:
Niño
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Korean Journal of Pediatrics
Año:
2015
Tipo del documento:
Artículo
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