Possible Association between -G308A Tumor Necrosis Factor-alpha Gene Polymorphism and Major Depressive Disorder / 신경정신의학
Journal of Korean Neuropsychiatric Association
;
: 189-193, 2003.
Artículo
en Coreano
| WPRIM
| ID: wpr-212972
ABSTRACT
OBJECTIVES:
The present study was to examine possible association between the -G308A tumor necrosis factor (TNF)-alpha gene polymorphism and major depressive disorder (MDD) in Korean.METHODS:
108 inpatients with MDD and 125 healthy controls participated in this study. Genotyping was performed by polymerase chain reaction-restriction fragment length polymorphism.RESULTS:
Genotype and allele distributions in patients with MDD (p=0.02, p=0.01, respectively), were significantly different from those of the controls.CONCLUSION:
The present study suggests that the -G308A TNF-alpha gene polymorphism may have a potential role for the susceptibility to MDD in Korean population.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Factor de Necrosis Tumoral alfa
/
Trastorno Depresivo Mayor
/
Alelos
/
Genotipo
/
Pacientes Internos
Límite:
Humanos
Idioma:
Coreano
Revista:
Journal of Korean Neuropsychiatric Association
Año:
2003
Tipo del documento:
Artículo
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