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Urea Synthesis in the Intact and in the Isolated Perfused Liver of the Biotin-Deficient Rats
Yonsei Medical Journal ; : 13-16, 1971.
Artículo en Inglés | WPRIM | ID: wpr-217149
ABSTRACT
Biotin-deficient rats were raised on a purified ration containing raw egg white plus avidin. Urea synthesis and excretion were compared between the biotin-deficient and the pair-fed control rats. 24hrurinary urea excretion and the specific activities of carbamylphosphate synthetase, ornithine transcarbamylase, and arginase in the liver mitochondria fraction were no different between these two groups. The net urea production in the liver slice and in the isolated perfused liver of the biotin-deficient rats was similar to that of the pair-fed control. Thus the conclusion must be that biotin is not in urea in mea biosynthesis in the rat.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Avitaminosis / Urea / Biotina / Hígado / Animales Límite: Animales Idioma: Inglés Revista: Yonsei Medical Journal Año: 1971 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Avitaminosis / Urea / Biotina / Hígado / Animales Límite: Animales Idioma: Inglés Revista: Yonsei Medical Journal Año: 1971 Tipo del documento: Artículo