Clinical Follow-Up Study for Brain Metastases of Renal Cell Carcinoma
Korean Journal of Urology
;
: 224-228, 2009.
Artículo
en Coreano
| WPRIM
| ID: wpr-218441
ABSTRACT
PURPOSE:
We reviewed the records of renal cell carcinoma (RCC) patients with brain metastases, analyzed about survival and prognosis after several palliative management. MATERIALS ANDMETHODS:
Between June 1998 and January 2008, 22 patients diagnosed to have brain metastases from RCC. We retrospectively reviewed their medical records, and analyzed clinical properties.RESULTS:
Of 278 patients with RCC, 22 patients (7.9%) diagnosed to have brain metastases. The pathological T stages and Fuhrman nuclear grade of RCC at the time of initial diagnosis were various (T1 1 patient, T2 5, T3 8, T4 3, Fuhrman grade 1 0, 2 4, 3 10, 4 6, unknown 2). Most of RCC was clear cell carcinoma (17/22). Most symptoms suggesting brain metastases were neurologic. Median cancer specific survival (CSS) of WBRT, radiosurgery, or surgery group (13/22) was 4 months, conservative management group (9/22) was 1.5 months and CSS of the former group was significantly better. Median duration of development of brain metastasis after diagnosis of RCC was 28 month (1-120). There was no difference in CSS between patients with brain metastasis developed before and after 28 month (p=0.361).CONCLUSIONS:
Brain metastases of RCC have poor prognostic course. Development interval of brain metastases did not affect survival. WBRT, radiosurgery or surgery group showed better survival. Active intervention may improve survival.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pronóstico
/
Encéfalo
/
Carcinoma de Células Renales
/
Registros Médicos
/
Estudios Retrospectivos
/
Estudios de Seguimiento
/
Radiocirugia
/
Metástasis de la Neoplasia
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Urology
Año:
2009
Tipo del documento:
Artículo
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