A case of Polymyositis with Involvement of Liver / 대한류마티스학회지

ABSTRACT

Polymyositis is non-hereditary, autoimmune rheumatic disease characterized by progressive symmetrical proximal muscle weakness due to chronic inflammation of skeletal muscles. Its definite causes are unknown, genetic and environmental factors including some viral infections such as hepatitis C virus were associated with development of autoimmunity. Clinical symptoms are symmetrical proximal muscle weakness, arthritis, interstitial lung disease, heart failure and gastrointestinal disturbance. We experienced a case of polymyositis which involved liver and developed chronic hepatitis confirmed by liver biopsy.