Primary Antiphospholipid Syndrome Presenting Dementia and Brain Atrophy
Journal of the Korean Neurological Association
;
: 561-566, 1993.
Artículo
en Coreano
| WPRIM
| ID: wpr-220521
ABSTRACT
Antiphospholipid antibody syndrome (APS) has been considered as a distinct clinical entity, usually associated with systemic lupus erythematosus (SLE) or with other connective tissue disease. Prominent clinical features include venous thrombosis, arterial occlusions, thrombocytopenia, hemolytic anemia, recurrent fetal loss, livedo reticularis and neurologic manifestations. Antiphospholipid antibodies (aPL) represent a spectrum of phospholipid-binding antibodies, including the lupus anticoagulant(LA), anticardiolipin antibody (aCL), and the biologic false-positive serologic test for syphilis (BFP-STS). Primary antiphospholipid syndrome (PAPS) which has been recently described is a complication of autoimmune aPL with lack of serologic and clinical features of SLE. We present a young female patient with PAPS who showed progressive dementia, diffuse cerebral atrophy, renal arteriolar occlusions, livedo reticularis, and valvular heart disease. To our knowledge, our patient is the first described with the clinical and mangetic resonance imaging(M-RI) findings in this entity.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Atrofia
/
Trombocitopenia
/
Encéfalo
/
Pruebas Serológicas
/
Sífilis
/
Síndrome Antifosfolípido
/
Anticuerpos Antifosfolípidos
/
Anticuerpos Anticardiolipina
/
Enfermedades del Tejido Conjuntivo
/
Trombosis de la Vena
Tipo de estudio:
Estudio diagnóstico
Límite:
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Neurological Association
Año:
1993
Tipo del documento:
Artículo
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