Amiodarone Induced Blue-gray Pigmentation / 대한피부과학회지
Korean Journal of Dermatology
;
: 375-377, 2009.
Artículo
en Coreano
| WPRIM
| ID: wpr-220746
ABSTRACT
Amiodarone (AD) is a benzofuran derivative that has been used for the treatment of recurrent arrhythmia and as a coronary vasodilator in Europe since 1964. AD-related hyperpigmentation develops after an average of 20 months of continuous AD treatment and with a minimal total dose of 160 g AD in less than 10% of the patients. A 49-year-old man presented with asymptomatic blue-gray patches that had slowly developed on the face over the previous 3 months. He had been taken amiodarone continuously for 39 months (cumulative dose 974 g). A skin lesion biopsy from the face showed many dermal melanophages containing brown granules. The AD was discontinued and he begin using sunscreen and is courrently being followed-up. The skin discoloration was still evident, but slightly diminished at five month's follow up.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Arritmias Cardíacas
/
Piel
/
Benzofuranos
/
Biopsia
/
Pigmentación
/
Estudios de Seguimiento
/
Hiperpigmentación
/
Europa (Continente)
/
Amiodarona
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Humanos
País/Región como asunto:
Europa
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Año:
2009
Tipo del documento:
Artículo
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