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A case of rifampicin-induced interstitial pneumonitis / 대한내과학회지
Korean Journal of Medicine ; : 592-596, 2008.
Artículo en Coreano | WPRIM | ID: wpr-222963
ABSTRACT
Rifampicin is a powerful agent for the treatment of pulmonary tuberculosis. However, it may induce several adverse effects, including rare cases of lung toxicity. Here, we report a case of rifampicin-induced interstitial pneumonitis. A 57-year-old woman diagnosed with cerebellar tuberculoma developed progressive dyspnea after the 5th day of anti-tuberculosis medication. Chest X-ray revealed newly developed ground glass opacities on both lower lung fields. Drug-induced pneumonitis was suspected and all anti-tuberculosis medications were halted. Transbronchial lung biopsy was consistent with desquamative interstitial pneumonitis. After clinical improvement, a rechallenge test with each anti-tuberculosis medication was attempted. No primary anti-tuberculosis drug except rifampicin triggered recurrence of symptoms, supporting a diagnosis of rifampicin-induced interstitial pneumonitis. Clinicians should be aware of this rare, but serious, side effect of rifampicin treatment.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Neumonía / Recurrencia / Rifampin / Tórax / Tuberculoma / Tuberculosis / Tuberculosis Pulmonar / Biopsia / Enfermedades Pulmonares Intersticiales / Disnea Límite: Femenino / Humanos Idioma: Coreano Revista: Korean Journal of Medicine Año: 2008 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Neumonía / Recurrencia / Rifampin / Tórax / Tuberculoma / Tuberculosis / Tuberculosis Pulmonar / Biopsia / Enfermedades Pulmonares Intersticiales / Disnea Límite: Femenino / Humanos Idioma: Coreano Revista: Korean Journal of Medicine Año: 2008 Tipo del documento: Artículo