The Analysis of Risk Factor and Infection Control of Carbapenem-Resistant Acinetobacter baumannii in a Medical Intensive Care Unit / 병원감염관리
Korean Journal of Nosocomial Infection Control
;
: 72-78, 2009.
Artículo
en Coreano
| WPRIM
| ID: wpr-223475
ABSTRACT
BACKGROUND:
An epidemiologic study was performed after the outbreak of carbapenem-resistant Acinetobacter baumannii (CRAB) in the medical intensive care unit (MICU) from December 2006 to May 2007.METHODS:
A retrospective case-control study was performed using the medical records of the patients. The case and control patients were compared for age, gender, total length of stay in MICU, prior carbapenem use, Acute Physiology and Chronic Health Evaluation II (APACH II) score, presence of central line, effect of mechanical ventilation, and sputum suction. Environmental and hand-washing studies were performed during the outbreak.RESULTS:
Ten CRAB-affected patients and 29 controls were enrolled in this study. Univariate analysis showed that the age, total length of stay in MICU, presence of central line, and prior carbapenem use were associated with the CRAB outbreak. However, multivariate analysis showed that only prior carbapenem use was associated with the CRAB outbreak (odd ratio 8.67, P=0.01). The outbreak disappeared after implementing a combined infection control strategy, including the sequential disinfection of MICU and strict compliance with cross-transmission prevention protocols.CONCLUSION:
The use of carbapenem was associated with an increased risk of CRAB infection. This study suggests that the MICU contamination and infection transmission by health-care workers played a major role in the CRAB outbreak. Novel strategies such as restricted use of broad-spectrum antibiotics, strict hand hygiene, strict isolation of the patients, and MICU disinfection may be required to prevent the CRAB outbreak.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Respiración Artificial
/
Esputo
/
Succión
/
Acinetobacter
/
Estudios Epidemiológicos
/
Estudios de Casos y Controles
/
Desinfección
/
Registros Médicos
/
Análisis Multivariante
/
Estudios Retrospectivos
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Factores de riesgo
Límite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Nosocomial Infection Control
Año:
2009
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS