Diffuse Alveolar Hemorrhage Associated with Antineutrophil Cytoplasmic Antibody levels in a Pregnant Woman Taking Propylthiouracil
The Korean Journal of Internal Medicine
;
: 240-243, 2006.
Artículo
en Inglés
| WPRIM
| ID: wpr-223935
ABSTRACT
Propylthiouracil (PTU) is known to be a potential cause of antineutrophil cytoplasmic antibody (ANCA) positive small vessel vasculitis, resulting in glomerulonephritis and diffuse alveolar hemorrhage (DAH). Herein, we describe a 25-year-old pregnant woman who developed a perinulcear ANCA (p-ANCA) and myeloperoxidase ANCA (MPO-ANCA) positive DAH during PTU therapy. The patient improved after corticosteroid therapy and discontinuation of the PTU. Methimazole was prescribed in spite of the risk of recurrence of DAH because of the pregnancy. The patient is currently free from pulmonary problems. Our case shows that the alternative agent, methimazole, can be used to treat hyperthyroidism in a pregnant patient with PTU associated DAH.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Complicaciones Hematológicas del Embarazo
/
Propiltiouracilo
/
Alveolos Pulmonares
/
Antitiroideos
/
Broncoscopía
/
Tomografía Computarizada por Rayos X
/
Anticuerpos Anticitoplasma de Neutrófilos
/
Diagnóstico Diferencial
/
Hemoptisis
/
Hipertiroidismo
Tipo de estudio:
Estudio diagnóstico
Límite:
Adulto
/
Femenino
/
Humanos
/
Embarazo
Idioma:
Inglés
Revista:
The Korean Journal of Internal Medicine
Año:
2006
Tipo del documento:
Artículo
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