Syndrome of inappropriate antidiuretic hormone secretion associated with seronegative neuromyelitis optica spectrum disorder
Kidney Research and Clinical Practice
;
: 100-104, 2017.
Artículo
en Inglés
| WPRIM
| ID: wpr-224468
ABSTRACT
The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a potential cause of hyponatremia of the central nervous system (CNS). Although SIADH has been reported to be associated with many other central nervous disorders, its association with neuromyelitis optica (NMO) or NMO spectrum disorders are rare. NMO is a demyelinating disorder characterized by optic neuritis and transverse myelitis. Aquaporin-4 (AQP4), which is the target antigen for a NMO autoantibody, is the predominant CNS water channel. However, some NMO patients show seronegative AQP4 antibody results. The spectrum of NMO has been changed, and new findings about the disease have been reported. Here, we report a case of seronegative NMO spectrum disorder associated with SIADH.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Agua
/
Sistema Nervioso Central
/
Neuritis Óptica
/
Neuromielitis Óptica
/
Enfermedades Desmielinizantes
/
Hiponatremia
/
Síndrome de Secreción Inadecuada de ADH
/
Mielitis Transversa
Límite:
Humanos
Idioma:
Inglés
Revista:
Kidney Research and Clinical Practice
Año:
2017
Tipo del documento:
Artículo
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