Allergen Sensitization Pattern by Sex: A Cluster Analysis in Korea
Annals of Dermatology
;
: 735-741, 2017.
Artículo
en Inglés
| WPRIM
| ID: wpr-225298
ABSTRACT
BACKGROUND:
Allergens tend to sensitize simultaneously. Etiology of this phenomenon has been suggested to be allergen cross-reactivity or concurrent exposure. However, little is known about specific allergen sensitization patterns.OBJECTIVE:
To investigate the allergen sensitization characteristics according to gender.METHODS:
Multiple allergen simultaneous test (MAST) is widely used as a screening tool for detecting allergen sensitization in dermatologic clinics. We retrospectively reviewed the medical records of patients with MAST results between 2008 and 2014 in our Department of Dermatology. A cluster analysis was performed to elucidate the allergen-specific immunoglobulin (Ig)E cluster pattern.RESULTS:
The results of MAST (39 allergen-specific IgEs) from 4,360 cases were analyzed. By cluster analysis, 39items were grouped into 8 clusters. Each cluster had characteristic features. When compared with female, the male group tended to be sensitized more frequently to all tested allergens, except for fungus allergens cluster.CONCLUSION:
The cluster and comparative analysis results demonstrate that the allergen sensitization is clustered, manifesting allergen similarity or co-exposure. Only the fungus cluster allergens tend to sensitize female group more frequently than male group.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Inmunoglobulinas
/
Alérgenos
/
Análisis por Conglomerados
/
Tamizaje Masivo
/
Registros Médicos
/
Estudios Retrospectivos
/
Dermatología
/
Hongos
/
Corea (Geográfico)
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
/
Estudio de tamizaje
Límite:
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Annals of Dermatology
Año:
2017
Tipo del documento:
Artículo
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