Isolation of Middle East Respiratory Syndrome Coronavirus from a Patient of the 2015 Korean Outbreak
Journal of Korean Medical Science
;
: 315-320, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-225574
ABSTRACT
During the 2015 outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) in Korea, 186 persons were infected, resulting in 38 fatalities. We isolated MERS-CoV from the oropharyngeal sample obtained from a patient of the outbreak. Cytopathic effects showing detachment and rounding of cells were observed in Vero cell cultures 3 days after inoculation of the sample. Spherical virus particles were observed by transmission electron microscopy. Full-length genome sequence of the virus isolate was obtained and phylogenetic analyses showed that it clustered with clade B of MERS-CoV.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Filogenia
/
Células Vero
/
ARN Viral
/
Microscopía Electrónica
/
Chlorocebus aethiops
/
Reacción en Cadena de la Polimerasa
/
Brotes de Enfermedades
/
Análisis de Secuencia de ARN
/
Infecciones por Coronavirus
/
República de Corea
Límite:
Animales
/
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Journal of Korean Medical Science
Año:
2016
Tipo del documento:
Artículo
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