Your browser doesn't support javascript.
loading
Pulmonary Cryptococcosis in Rheumatoid Arthritis Patient Treated With Leflunomide
Journal of the Korean Geriatrics Society ; : 232-236, 2014.
Artículo en Coreano | WPRIM | ID: wpr-226413
ABSTRACT
Leflunomide, a disease-modifying antirheumatic drug, is effective for rheumatoid arthritis as monotherapy or combination therapy with methotrexate. The most common adverse effects are diarrhea, dyspepsia, nausea, abdominal pain, oral ulcer, hepatotoxicity, skin rash, hypertension, weight loss, and interstitial lung disease. The occurrence of pulmonary cryptococcosis in leflunomide treatment has not been reported in Korea. A 74-year-old woman was admitted to hospital due to asymptomatic pulmonary nodule. She was diagnosed rheumatoid arthritis and treated with leflunomide 5 months ago due to treatment failure with methotrexate, hydroxychloroquine, and sulfasalazine. Chest radiograph and computed tomography showed solitary pulmonary nodule in her right lower lung. Pulmonary cryptococcosis was confirmed by needle biopsy of lung stained with Gomori methenamine silver and mucicarmine. The lesion was improved after antifungal therapy for 3 months.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Artritis Reumatoide / Sulfasalazina / Biopsia con Aguja / Radiografía Torácica / Pérdida de Peso / Dolor Abdominal / Metotrexato / Insuficiencia del Tratamiento / Nódulo Pulmonar Solitario / Enfermedades Pulmonares Intersticiales Límite: Anciano / Femenino / Humanos País/Región como asunto: Asia Idioma: Coreano Revista: Journal of the Korean Geriatrics Society Año: 2014 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Artritis Reumatoide / Sulfasalazina / Biopsia con Aguja / Radiografía Torácica / Pérdida de Peso / Dolor Abdominal / Metotrexato / Insuficiencia del Tratamiento / Nódulo Pulmonar Solitario / Enfermedades Pulmonares Intersticiales Límite: Anciano / Femenino / Humanos País/Región como asunto: Asia Idioma: Coreano Revista: Journal of the Korean Geriatrics Society Año: 2014 Tipo del documento: Artículo