Intrauterine therapy for macrocystic congenital cystic adenomatoid malformation of the lung
Obstetrics & Gynecology Science
;
: 102-108, 2014.
Artículo
en Inglés
| WPRIM
| ID: wpr-228434
ABSTRACT
OBJECTIVE:
To report on our experiences with thoracoamniotic shunting and/or the injection of a sclerosing agent (OK-432) to treat fetuses diagnosed with macrocystic congenital cystic adenomatoid malformation (CCAM) of the lung.METHODS:
A retrospective study was undertaken in six fetuses with macrocystic CCAM at our institute that had been confirmed by postnatal surgery between August 1999 and January 2012.RESULTS:
Six fetuses that had been diagnosed with macrocystic CCAM were analyzed. The median gestational age at diagnosis was 23.5 weeks (range, 19.5-31.0 weeks), and at the time of primary treatment was 24.0 weeks (range, 20.5-31.0 weeks). The mean size of the largest cyst at the initial assessment was 42.5+/-15 mm. Four fetuses were associated with mediastinal shifting, and one also showed fetal hydrops. All fetuses underwent a shunting procedure within the cysts, one case among them was also treated with OK-432. After the completion of all procedures, the mean size of the largest cyst was all decreased (14.2+/-12 mm). The median gestational age at delivery was 38.0 weeks (range, 32.4-40.3 weeks). All of the newborns underwent the surgical resection at a median age of 6 days (range, 1-136 days) and are currently doing well without any complications.CONCLUSION:
We suggest that intrauterine decompression therapy to manage fetal macrocystic CCAM is recommendable treatment for good perinatal outcome.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Picibanil
/
Diagnóstico Prenatal
/
Soluciones Esclerosantes
/
Hidropesía Fetal
/
Malformación Adenomatoide Quística Congénita del Pulmón
/
Estudios Retrospectivos
/
Edad Gestacional
/
Descompresión
/
Terapias Fetales
/
Diagnóstico
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
Límite:
Humanos
/
Recién Nacido
Idioma:
Inglés
Revista:
Obstetrics & Gynecology Science
Año:
2014
Tipo del documento:
Artículo
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