Acanthamoeba Keratitis Related to Orthokeratology Contact Lens

ABSTRACT

PURPOSE: To report 4 cases of Acanthamoeba keratitis related to orthokeratology lens overnight wear. METHODS: Four patients had histories of overnight orthkeratology lens wear of 10 months to 3 years when they presented with corneal ulcers. RESULTS: The organism isolated by corneal scraping was Aanthamoeba. The patients were treated with polyhexamethylene biguanide (PHMB), and chlorhexidine, resulting in a resolution of ocular inflammation. CONCLUSION: The risk of Acanthamoeba keratitis as a potential complication of overnight orthkeratology should be considered.