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Prevalence and Clinical Manifestations of Malaria in Aligarh, India
The Korean Journal of Parasitology ; : 621-629, 2014.
Artículo en Inglés | WPRIM | ID: wpr-229075
ABSTRACT
Malaria is one of the most widespread infectious diseases of tropical countries with an estimated 207 million cases globally. In India, there are endemic pockets of this disease, including Aligarh. Hundreds of Plasmodium falciparum and P. vivax cases with severe pathological conditions are recorded every year in this district. The aim of this study is to find out changes in liver enzymes and kidney markers. Specific diagnosis for P. falciparum and P. vivax was made by microscopic examination of Giemsa stained slides. Clinical symptoms were observed in both of these infections. Liver enzymes, such as AST, ALT, and ALP, and kidney function markers, such as creatinine and urea, were estimated by standard biochemical techniques. In Aligarh district, P. vivax, P. falciparum, and mixed infections were 64%, 34%, and 2%, respectively. In case of P. falciparum infection, the incidences of anemia, splenomegaly, renal failure, jaundice, and neurological sequelae were higher compared to those in P. vivax infection. Recrudescence and relapse rates were 18% and 20% in P. falciparum and P. vivax infections, respectively. Liver dysfunctions and renal failures were more common in P. falciparum patients, particularly in elderly patients. Artesunate derivatives must, therefore, be introduced for the treatment of P. falciparum as they resist to chloroquine as well as sulfadoxine-pyrimethamine combinations.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Recurrencia / Prevalencia / Malaria Vivax / Malaria Falciparum / Técnicas de Laboratorio Clínico / India / Riñón / Enfermedades Renales / Pruebas de Función Renal / Hígado Tipo de estudio: Estudio diagnóstico / Estudio de prevalencia Límite: Adolescente / Adulto / Anciano / Aged80 / Niño / Child, preschool / Femenino / Humanos / Lactante / Masculino País/Región como asunto: Asia Idioma: Inglés Revista: The Korean Journal of Parasitology Año: 2014 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Recurrencia / Prevalencia / Malaria Vivax / Malaria Falciparum / Técnicas de Laboratorio Clínico / India / Riñón / Enfermedades Renales / Pruebas de Función Renal / Hígado Tipo de estudio: Estudio diagnóstico / Estudio de prevalencia Límite: Adolescente / Adulto / Anciano / Aged80 / Niño / Child, preschool / Femenino / Humanos / Lactante / Masculino País/Región como asunto: Asia Idioma: Inglés Revista: The Korean Journal of Parasitology Año: 2014 Tipo del documento: Artículo