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Polymyositis as a manifestation of chronic graft-versus-host disease after allogeneic bone marrow transplantation / 대한내과학회지
Korean Journal of Medicine ; : 110-113, 2009.
Artículo en Coreano | WPRIM | ID: wpr-229423
ABSTRACT
Chronic graft-versus-host disease (cGVHD) remains one of the major complications of allogeneic hematopoietic stem cell transplantation. Although cGVHD has various manifestations in almost all organs, cases of cGVHD involving skeletal muscle are rare. We experienced a 26-year-old man with polymyositis with no other concurrent cGVHD after HLA-matched myeloablative transplantation for acute myelogenous leukemia. He had a history of acute and chronic GVHD. The patient complained of fever and myalgia 3 years after transplantation. The serum creatine kinase (CK, 2,223 IU/L) and aldolase (87.6 sigmaU/mL) were elevated. The muscle biopsy and electromyographic findings were consistent with myositis with necrosis. His condition improved dramatically with immunosuppressive therapy. Although muscle involvement, alone, in cGVHD is very rare, early diagnosis and proper treatment are still important.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Biopsia / Médula Ósea / Leucemia Mieloide Aguda / Trasplante de Médula Ósea / Polimiositis / Músculo Esquelético / Trasplante de Células Madre Hematopoyéticas / Trasplantes / Creatina Quinasa / Diagnóstico Precoz Tipo de estudio: Estudio diagnóstico / Estudio de tamizaje Límite: Adulto / Humanos Idioma: Coreano Revista: Korean Journal of Medicine Año: 2009 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Biopsia / Médula Ósea / Leucemia Mieloide Aguda / Trasplante de Médula Ósea / Polimiositis / Músculo Esquelético / Trasplante de Células Madre Hematopoyéticas / Trasplantes / Creatina Quinasa / Diagnóstico Precoz Tipo de estudio: Estudio diagnóstico / Estudio de tamizaje Límite: Adulto / Humanos Idioma: Coreano Revista: Korean Journal of Medicine Año: 2009 Tipo del documento: Artículo