Structure and function of apolipoprotein and prevention and therapy of virus diseases / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 448-451, 2007.
Artículo
en Chino
| WPRIM
| ID: wpr-229956
ABSTRACT
Apolipoprotein, an important component of the lipoproteins, modulates the activity of enzyme, introduces the binding of cell receptor and lipoproteins, and keeps the structural stability of lipoproteins. The amphipathic helices structure in apolipoproteins is the structural basis that it binds and transports lipids. A certain envelope glycoprotein (gp) in the outer membrane of HIV also has been found to be with such amphipathic helices structure. Recent studies have shown that the liposome consisted of apolipoproteins and phospholipids may defend against HCV, HIV, and herpes simplex virus, and even neutralize the endotoxin released by bacteria. The liposome made up of apolipoproteins and phospholipid has became a potential carrier for anti-tumor and anti-virus drugs.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Antivirales
/
Apolipoproteínas
/
Fosfolípidos
/
Fisiología
/
Conformación Proteica
/
Virosis
/
Terapia Genética
/
Química
/
Quimioterapia
/
Liposomas
Límite:
Animales
/
Humanos
Idioma:
Chino
Revista:
Acta Academiae Medicinae Sinicae
Año:
2007
Tipo del documento:
Artículo
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