Clinical study on treatment of chronic superficial gastritis with jinghua weikang capsule / 中国中西医结合杂志

ABSTRACT

<p><b>OBJECTIVE</b>To observe the clinical efficacy and safety of Jinghua Weikang Capsule (JWC) on chronic gastritis (CG).</p><p><b>METHODS</b>Ninety patients with CG were randomly divided into 3 groups the control group treated with domperidone 10 mg, 3 times per day orally, the high and low-dose JWC groups treated with JWC 160 mg and 80 mg respectively 3 times per day. The therapeutic course for all groups was 14 days. Dyspeptic symptom score, gastric emptying rate and quality of life (QOL) in patients were observed.</p><p><b>RESULTS</b>Dyspeptic symptom score was 19.97 +/- 1.85 and 24.40 +/- 1.85 after treatment in high and low-dose JWC groups respectively, lower than that before treatment (28.33 +/- 1.88 and 27.70 +/- 1.68, P <0.05); QOL improved obviously in all the three groups, among which the high-dose JWC group showed the best effect. The adverse reaction of JWC was very mild.</p><p><b>CONCLUSION</b>JWC is an effective and safe drug for alleviating dyspeptic symptoms in patients with CG, its effect is more evident when high dose is applied.</p>