Your browser doesn't support javascript.
loading
On the relationship between serum total adiponectin and insulin resistance in polycystic ovary syndrome / 生物医学工程学杂志
Journal of Biomedical Engineering ; (6): 636-640, 2010.
Artículo en Chino | WPRIM | ID: wpr-230814
ABSTRACT
It is the intent of this investigation to gain an insight into the relationship of serum total adiponectin with polycystic ovary syndrome (PCOS) and insulin resistance. Fifty-eight PCOS patients were enrolled (29 with high serum insulin level and 29 without), at the same time, 29 non-PCOS women with normal weight were included as control. The influencing factors of total adiponectin, PCOS and insulin resistance were analyzed. The serum total adiponectin of PCOS patients and all participants were found to be negatively related to waist hip ratio (r = -0.39, r = -0.36) and InHOMA-IR (r = -0.53, r = -0.45), respectively. Adiponectin was not a protective factor of PCOS (P > 0.1), but it was that of PCOS-insulin resistance (OR = 0.81; 95% CI 0.67-0.97; P = 0.02). LH/FSH (OR = 1.51; 95% CI 1.16-1.96; P = 0.01) and InHOMA-IR (OR = 1.26; 95% CI 1.10-1.44; P = 0.01) were risk factors of PCOS, and waist hip ratio was that of PCOS-insulin resistance (OR = 8.57; 95% CI, 2.14-34.30, P = 0.01). Adiponectin might influence fasting insulin and InHOMA-IR (B = -0.22, P = 0.001; B = -0.02, P = 0.002). These data signify that adiponectin is not directly related with PCOS, but it is related with PCOS-HL Adiponectin might participate in the pathophysiologic mechanism of PCOS by influencing insulin sensitivity.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Fisiología / Síndrome del Ovario Poliquístico / Sangre / Resistencia a la Insulina / Relación Cintura-Cadera / Adiponectina Límite: Adulto / Femenino / Humanos Idioma: Chino Revista: Journal of Biomedical Engineering Año: 2010 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Fisiología / Síndrome del Ovario Poliquístico / Sangre / Resistencia a la Insulina / Relación Cintura-Cadera / Adiponectina Límite: Adulto / Femenino / Humanos Idioma: Chino Revista: Journal of Biomedical Engineering Año: 2010 Tipo del documento: Artículo