Immunity of peritoneal monocytes against Plasmodium yoelii infected erythrocytes / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 415-417, 2004.
Artículo
en Chino
| WPRIM
| ID: wpr-231917
ABSTRACT
<p><b>OBJECTIVE</b>To test the immunity of peritoneal monocytes against Plasmodium yoelii infected red blood cells (target cells).</p><p><b>METHODS</b>Saponinized Plasmodium yoelii infected red blood cells (SPRBC, Ghost erythrocyte) were used to immunize mice i.p twice. Three weeks later, the infected red blood cells were injected i.p.; 90 min later, the total peritoneal cells were isolated and washed for scanning electromicroscopy to observe the effects of the peritoneal monocyte to the target cell.</p><p><b>RESULTS</b>The peritoneal cells of the immunized mice were activated after 90 min of the challenge of target cells. The size of the cell was not even and the pili on the cell surface turned to be long and densed. Cell interconnections were found among the cells. In some peritoneal monocytes, their cell plasma were scattered (omlette-like) or with the shape as "cellular bomb". The scattered or the sheeted pili and spredding cell plasma could adhere to the target cells which were perforated densely and damaged.</p><p><b>CONCLUSION</b>The protective adaptive immunity exists in the peritoneal monocytes of immunized mice.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Parasitología
/
Peritoneo
/
Anticuerpos Antiprotozoarios
/
Plasmodium yoelii
/
Monocitos
/
Vacunas contra la Malaria
/
Biología Celular
/
Alergia e Inmunología
/
Membrana Eritrocítica
/
Ratones Endogámicos BALB C
Límite:
Animales
Idioma:
Chino
Revista:
Acta Academiae Medicinae Sinicae
Año:
2004
Tipo del documento:
Artículo
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