Role of RASSF1A hypermethylation in prostate cancer / 中华男科学杂志
National Journal of Andrology
;
(12): 822-825, 2007.
Artículo
en Chino
| WPRIM
| ID: wpr-232054
ABSTRACT
RASSF1A gene cloned from 3p21.3 region is a novel candidate tumor suppressor gene. The aberrant methylation of CpG lands in the promoter region is the major inactivation mechanism of RASSF1A, and is significantly involved in the genesis and development of multiple solid tumors including prostate cancer. The methylation status examination of RASSF1A could serve as an important technique for the early diagnosis of prostate cancer, while methylation inhibitor is likely to become a novel therapeutic agent.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Neoplasias de la Próstata
/
Metilación de ADN
/
Proteínas Supresoras de Tumor
/
Diagnóstico Precoz
/
Diagnóstico
/
Genética
Tipo de estudio:
Estudio diagnóstico
/
Estudio de tamizaje
Límite:
Humanos
/
Masculino
Idioma:
Chino
Revista:
National Journal of Andrology
Año:
2007
Tipo del documento:
Artículo
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