Study on the clinical epidemiology of systemic lupus erythematosus among 1433 cases / 中华流行病学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To explore factors that affecting the outcome of systemic lupus erythematosus (SLE) therapy.</p><p><b>METHODS</b>Factors on the results of therapy were analysed through a case-control study.</p><p><b>RESULTS</b>The common symptoms of SLE were fever, joint pain and skin eruption on face while the common provocation factors of SLE were infection and birth. Through multivariate logistic regression analyses, factors that influencing SLE result of treatment were tachycardia, diastolic pressure step-up, complement C(3) reduction, anti-ds-DNA antibody, SLE relapse and brain syndrome with the OR values as 2.28, 2.34, 2.42, 2.47, 1.98 and 5.56, respectively.</p><p><b>CONCLUSION</b>The symptom and clinical characteristics of SLE were complicated. SLE treatment result could be influenced by tachycardia, diastolic pressure step-up, complement C(3) reduction, anti-ds-DNA antibody, SLE relapse and brain syndrome suggesting that the prognosis of SLE patients should be comprehensively considered.</p>