The effects of 4 laboratory test kits in early detecting of severe acute respiratory syndrome coronavirus / 中华流行病学杂志
Chinese Journal of Epidemiology
;
(12): 22-24, 2005.
Artículo
en Chino
| WPRIM
| ID: wpr-232142
ABSTRACT
<p><b>OBJECTIVE</b>To compare the 4 test kits on severe acute respiratory syndrome coronavirus (SARS-CoV) gene, antigen and antibody for early diagnose of SARS patients.</p><p><b>METHODS</b>Three enzyme linked immunosorbent assay (ELISA) kits were used to detect SARS-CoV IgG, IgM and N protein and fluorescent polymerase chain reaction (F-PCR) kit was used to detect SARS-CoV RNA.</p><p><b>RESULTS</b>In 162 serum samples, 90.2% (55/61) became N protein positive in 1 - 5 days and 92.8% (13/14) became positive IgM and IgG in 15 - 18 days after the onset of disease, respectively. On 82 gorgling samples, the positive rates of F-PCR were 56.3% (14/24) in 1 - 5 days and 71.4% (10/14) in 6 - 9 days after the onset.</p><p><b>CONCLUSION</b>Other than F-PCR, N protein had good effect in the early detection on dubious patients which could lead to effective prevention and control of the epidemic.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Juego de Reactivos para Diagnóstico
/
Estándares de Referencia
/
Virología
/
Sangre
/
ARN Viral
/
Ensayo de Inmunoadsorción Enzimática
/
Reacción en Cadena de la Polimerasa
/
Proteínas de la Nucleocápside
/
Síndrome Respiratorio Agudo Grave
/
Coronavirus Relacionado al Síndrome Respiratorio Agudo Severo
Tipo de estudio:
Estudio diagnóstico
/
Estudio de tamizaje
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Epidemiology
Año:
2005
Tipo del documento:
Artículo
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