Study on the risk factors leading to irregularly anti-pulmonary tuberculosis drug taking in patients with smear positive / 中华流行病学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To describe the current situation and explore risk factors to irregularly antipulmonary tuberculosis(TB) drugs taking in smear positive TB patients.</p><p><b>METHODS</b>Four out of the forty counties in Chongqing were randomly sampled according to the levels of social and economic development. Totally, 405 new patients with smear positive tuberculosis were systematically sampled and a household survey was carried out. A multiple logistic regression model was fitted to explore the risk factors to irregularly anti-TB drugs taking.</p><p><b>RESULTS</b>Of valid 401 cases, 50 (12.47%) did not take their drugs regularly and the top 3 reasons for irregular drugs taking were (1) Adverse effects; (2)Economic hardship; (3) Stopped taking drugs when symptom disappeared. Results from multiple logistic regression analysis showed that factors as self-perceived economical burden, awareness on TB before being infected and awareness on the fact that if anti-TB drugs can be stopped if the symptoms disappeared, were statistically significant to irregularly drugs taking.</p><p><b>CONCLUSION</b>Strengthening health education program and alleviation of economical burden might serve as two effective measures for regularly drugs taking among TB patients.</p>