Auditory brainstem response in normal guinea pigs and those with gentamicin-induced hearing loss under awake and anesthetic conditions / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1596-1598, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-232829
ABSTRACT
<p><b>OBJECTIVE</b>To observe the alterations of auditory brainstem response (ABR) in guinea pigs with gentamicin-induced hearing loss under awake and anesthetic conditions.</p><p><b>METHODS</b>We recorded the ABR in 20 normal guinea pigs and 20 with gentamicin-induced hearing loss before and after anesthesia for statistical analysis.</p><p><b>RESULTS</b>No significant difference was observed in the waveform, response threshold (RT), I and III peak latencies (PL), I-III interpeak latencies (IPL) of ABR between awake and anesthetic conditions in normal guinea pigs (P>0.05), nor did gentamicin-induced hearing loss showed obvious impact on the ABR parameters (P>0.05).</p><p><b>CONCLUSION</b>No significant ABR alterations occur under awake and anesthetic conditions in either normal guinea pigs or those with hearing loss, therefore ABR test can be performed without anesthesia to ensure the success and error minimization of the experiment.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
Vigilia
/
Gentamicinas
/
Distribución Aleatoria
/
Potenciales Evocados Auditivos del Tronco Encefálico
/
Cobayas
/
Pérdida Auditiva Bilateral
/
Anestesia
Límite:
Animales
Idioma:
Chino
Revista:
Journal of Southern Medical University
Año:
2006
Tipo del documento:
Artículo
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