Design and manufacture of microneedles array for transdermal drug delivery / 中国医疗器械杂志
Chinese Journal of Medical Instrumentation
;
(6): 33-38, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-232895
ABSTRACT
It is very important to disrupt the stratum corneum structure and to create pathways allowing transport of macromolecules, as the traditional transdermal drug delivery has been severely limited by the skin barrier. With the development of the Micro Electro-Mechanical System (MEMS), it becomes possible for microneedles array to strengthen the transdermal drug delivery. In addition to the increase of the skin permeability, it can also be used to deliver drugs into skin, such as insulin and vaccine, providing a new direction for drug delivery systems. In this paper, we review the development and applications in transdermal drug delivery of microneedles' array. The commercial prospects and recommendations for the future research work are also represented.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Administración Cutánea
/
Sistemas de Liberación de Medicamentos
/
Diseño de Equipo
/
Sistemas Microelectromecánicos
/
Microinyecciones
/
Agujas
Idioma:
Chino
Revista:
Chinese Journal of Medical Instrumentation
Año:
2006
Tipo del documento:
Artículo
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