Diterpene constituents of Tripterygium willfordii (II) / 药学学报
Acta Pharmaceutica Sinica
;
(12): 942-945, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-233072
ABSTRACT
In order to study the constituents and pharmacology of Tripterygium plants (Tripterygium willfordii Hook.f), a variety of chromatography methods were used. Four compounds were isolated from Tripterygium plant and their structures were elucidated by UV, IR, MS, HR-MS, 1H NMR, 13C NMR and 2D-NMR techniques. The isolated compounds were named as triptonide (1), neo-triptetraolide (2), 2alpha-hydroxytriptonide (3), and 15-hydroxytriptonide (4), separately. Compounds 3, 4 belong to new diterpenoids, which can inhibit the growth of K562 cells (leukemia cells) and HL60 cells (acute myeloid leukemia cells).
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Plantas Medicinales
/
Triterpenos
/
Medicamentos Herbarios Chinos
/
Estructura Molecular
/
Química
/
Raíces de Plantas
/
Células HL-60
/
Células K562
/
Tripterygium
Límite:
Humanos
Idioma:
Chino
Revista:
Acta Pharmaceutica Sinica
Año:
2011
Tipo del documento:
Artículo
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