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Bone marrow necrosis as an initial manifestation of Philadelphia chromosome and myeloid antigens positive B acute lymphoblastic leukemia--a case report / 中国实验血液学杂志
Journal of Experimental Hematology ; (6): 832-834, 2006.
Artículo en Chino | WPRIM | ID: wpr-233484
ABSTRACT
Many diseases cause bone marrow necrosis (BMN), especially lymphocytic leukemia. To explore the complexity of the pathogenesis and pathology of BMN and understand the multiplicity of clinical features, a case of Philadelphia chromosome positive (Ph+) B acute lymphoblastic leukemia (ALL) expressing myeloid antigens was reported. The results indicated that the clinical features of this case were complicated and multiplex, the diagnosis was confirmed by using bone marrow smear and biopsy, immunophenotype analysis, conventional cytogenetics and fluorescence in situ hybridization (FISH), the prognosis of patients improved by active treatment for primary disease. In conclusion, the Ph+ B ALL expressing myeloid antigen with BMN is very rare, its diagnosis should be confirmed by using multiple methods, and the active treatments should be performed.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Patología / Sangre / Médula Ósea / Enfermedades de la Médula Ósea / Cromosoma Filadelfia / Inmunofenotipificación / Linfoma de Burkitt / Alergia e Inmunología / Genética / Necrosis Tipo de estudio: Estudio pronóstico Límite: Adulto / Femenino / Humanos Idioma: Chino Revista: Journal of Experimental Hematology Año: 2006 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Patología / Sangre / Médula Ósea / Enfermedades de la Médula Ósea / Cromosoma Filadelfia / Inmunofenotipificación / Linfoma de Burkitt / Alergia e Inmunología / Genética / Necrosis Tipo de estudio: Estudio pronóstico Límite: Adulto / Femenino / Humanos Idioma: Chino Revista: Journal of Experimental Hematology Año: 2006 Tipo del documento: Artículo