Regulatory effects of Bmi-1 gene on self-renewal of hematopoietic stem cells--review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 413-415, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-233578
ABSTRACT
Self-renewal of hematopoietic stem cells is vital for the sustained daily production of blood cells. The Bmi-1 gene is a putative oncogene belonging to the Polycomb group family. Recent studies have shown that the Polycomb-group gene Bmi-1 is indispensable for regulation of self-renewal of normal and leukemic stem cells. The research progress on structure and function of Bmi-1 gene, and its role in self-renewal of hematopoietic stem cells was reviewed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
Proteínas Represoras
/
Células Madre Hematopoyéticas
/
Proteínas Nucleares
/
Diferenciación Celular
/
División Celular
/
Proteínas Proto-Oncogénicas
/
Biología Celular
/
Complejo Represivo Polycomb 1
/
Genética
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Experimental Hematology
Año:
2006
Tipo del documento:
Artículo
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