Effect of nutritional status during infancy and childhood on the risk of overweight and obesity in adulthood / 中华流行病学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To examine the association between fetal nutritional status and overweight and obesity in their adulthood and to provide evidence for formulation of the strategy on preventing low birth weight.</p><p><b>METHODS</b>Using data from 2002 Nationwide Nutrition and Health Survey to set up a case-control method in order to compare body mass index(BMI), prevalence of overweight and obesity as well as to calculate odds ratio of overweight and obesity of case group compared with control group. Three case groups were selected from those who were born in 1959, 1960,1961 respectively, and the controls were those who were born in 1964.</p><p><b>RESULTS</b>The health consequence of being famines on adulthood was evident in women. Means of BMI in women were significantly higher in three case groups than that in control group(P<0.01). After adjustment on geographic regions, the prevalence of overweight in women was significantly higher in three case groups than that in control group(P< 0.01). The prevalence rates of obesity were significantly higher in 1959, 1960 groups than 1964 group(P< 0.05). The odds ratios of overweight of women in three case groups were 28.9% (95% CI1.063-1.565), 37.2% (95% CI1. 136-1.658) and 35.2% (95% CI 1. 103-1.657) respectively, all higher than that in the control group. The odds ratios of obesity of women born in 1959, 1960 groups were 46.5% (95% CI 1.088-1.972) and 39.6% (95% CI 1.039- 1.876) respectively, higher than that in the 1964 group. However, such differences were not found in men.</p><p><b>CONCLUSION</b>Higher risks of overweight and obesity in women were caused by malnutrition during their fetal lives. A strategy on preventing low birth weight should be formulated by the government to prevent the chronic disease in adulthood.</p>