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Comparison of prognostic models for patients with early-stage diffuse large B-cell lymphoma / 中华血液学杂志
Chinese Journal of Hematology ; (12): 269-272, 2016.
Artículo en Chino | WPRIM | ID: wpr-234006
ABSTRACT
<p><b>OBJECTIVE</b>To compare the prognostic value of different models in patients with early-stage diffuse large B-cell lymphoma (DLBCL).</p><p><b>METHODS</b>Early-stage DLBCL patients diagnosed from January 2000 to December 2012 were analyzed retrospectively. All patients received with at least 2 cycles of immunochemotherapy R-CHOP regimen (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone) with or without radiotherapy. The prognostic value of international prognostic index (IPI) , revised IPI (R-IPI) and enhanced IPI (NCCN-IPI) was compared.</p><p><b>RESULTS</b>Ninety-seven cases of early-stage DLBCL were included in the study. The median age was 58 years (15-88 years) with a median follow-up of 34.7 months (range 7.3-77.4 months). The expected 5-year overall survival (OS) for entire group was 82%. There was no patient in the high risk group according to IPI or NCCN-IPI. According to IPI, the 5-year OS in the low, low intermediate, high intermediate risk groups were 95%, 38% and 60%, respectively. According to R-IPI, the 5-year OS in the very good, good, and poor risk groups were 93%, 75% and 60%, respectively. According to NCCN-IPI, the 5-year OS in the low, low intermediate, high intermediate risk groups were 92%, 85% and 29%, respectively.</p><p><b>CONCLUSION</b>NCCN-IPI would be of an ideal prognostic model for early-stage DLBCL patients.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Pronóstico / Vincristina / Prednisona / Protocolos de Quimioterapia Combinada Antineoplásica / Doxorrubicina / Estudios Retrospectivos / Linfoma de Células B Grandes Difuso / Ciclofosfamida / Diagnóstico / Anticuerpos Monoclonales de Origen Murino Tipo de estudio: Estudio diagnóstico / Estudio observacional / Estudio pronóstico Límite: Adolescente / Adulto / Anciano / Aged80 / Humanos Idioma: Chino Revista: Chinese Journal of Hematology Año: 2016 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Pronóstico / Vincristina / Prednisona / Protocolos de Quimioterapia Combinada Antineoplásica / Doxorrubicina / Estudios Retrospectivos / Linfoma de Células B Grandes Difuso / Ciclofosfamida / Diagnóstico / Anticuerpos Monoclonales de Origen Murino Tipo de estudio: Estudio diagnóstico / Estudio observacional / Estudio pronóstico Límite: Adolescente / Adulto / Anciano / Aged80 / Humanos Idioma: Chino Revista: Chinese Journal of Hematology Año: 2016 Tipo del documento: Artículo