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Clinical study on treatment of patients with ankylosing spondylitis by Panlongqi tablet / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine ; (12): 540-542, 2007.
Artículo en Chino | WPRIM | ID: wpr-234775
ABSTRACT
<p><b>OBJECTIVE</b>A 6-month observation on curative effect of Panlongqi Tablet (PLQ) in treating patients with ankylosing spondylitis (AS) was conducted for evaluating its efficacy and safety.</p><p><b>METHODS</b>One hundred and four inpatients and outpatients with AS were randomly assigned to two groups by using random number table, 52 in each group. All patients were treated non-steroid anti-inflammatory drug (NSAID) and sulfasalazine (SSZ), and those in the treated group were given with PLQ additionally. The change of symptoms and signs were observed, and some laboratory indexes as Bath AS disease activity index (BASDAI), Bath AS functional index (BASFI), erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), as well as adverse reaction were observed as well. The revisit and follow-up study were carried out at the 3 months and 6 months respectively.</p><p><b>RESULTS</b>The lumbosacral pain was significantly alleviated, the time for lumbodorsal morning stiffness was shortened, the levels of BASDAI, BASFI, ESR and CRP were significantly lowered after treatment for 3 months or 6months (P < 0.05), and these improvements were more significant in the treated group as compared with those in the control group (P < 0.05). The main adverse reactions was dominantly the gastrointestinal symptoms, which showed insignificant difference between the two groups (P >0.05).</p><p><b>CONCLUSION</b>PLQ is an effective traditional medicine for AS with mild adverse reaction, it can be used as an adjuvant therapy.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Sulfasalazina / Espondilitis Anquilosante / Comprimidos / Medicamentos Herbarios Chinos / Antiinflamatorios no Esteroideos / Resultado del Tratamiento / Usos Terapéuticos / Quimioterapia / Quimioterapia Combinada / Fitoterapia Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Adolescente / Adulto / Femenino / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Integrated Traditional and Western Medicine Año: 2007 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Sulfasalazina / Espondilitis Anquilosante / Comprimidos / Medicamentos Herbarios Chinos / Antiinflamatorios no Esteroideos / Resultado del Tratamiento / Usos Terapéuticos / Quimioterapia / Quimioterapia Combinada / Fitoterapia Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Adolescente / Adulto / Femenino / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Integrated Traditional and Western Medicine Año: 2007 Tipo del documento: Artículo