Separation and purification processes of alkaloids from Lotus plumule with macroporous adsorption resin / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To explore the optimal separation of the alkaloids from Lotus plumule by selecting appropriate macroporous adsorption resins.</p><p><b>METHOD</b>To evaluated the separating efficiency by measuring the adsorption ratio, eluting ratio and the concentration of neferine.</p><p><b>RESULT</b>The LSA -5B macroporous adsorption resin prolided the optimal separating efficiency. The best adsorption capacity was achieved with the following conditions the concentration of extact liquid was 0. 125 g x mL(-1) (equivalence to raw material), then the resin was washed by water to remove impurity and alkaloids were desorbed by 50% ethanol.</p><p><b>CONCLUSION</b>This method is simple, feasible and suitable for industry production.</p>