Risk factors for parenteral nutrition-associated cholestasis in preterm infants / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 254-258, 2013.
Artículo
en Chino
| WPRIM
| ID: wpr-236826
ABSTRACT
<p><b>OBJECTIVE</b>To investigate risk factors for parenteral nutrition-associated cholestasis (PNAC) in preterm infants.</p><p><b>METHODS</b>A retrospective case-control study was performed on 244 preterm infants who received parenteral nutrition (PN) for over 14 days from January 2000 to October 2011.</p><p><b>RESULTS</b>Compared with those without PNAC (n=221), preterm infants with PNAC (n=23) had a longer total duration of PN, a higher total amino acid intake, a higher total lipid intake, a higher maximum daily amino acid intake, a higher maximum daily lipid intake, a higher intravenous calorie intake on the 14th day of PN, a lower birth weight and higher incidence rates of neonatal infection and anemia. Compared with those with PNAC, preterm infants without PNAC who showed a higher total amino acid intake also had a higher total lipid intake, a longer total duration of PN, a higher rate of mechanical ventilation and a lower gestational age. The preterm infants without PNAC who showed a higher total lipid intake also had a lower gestational age. Preterm infants without PNAC who showed a longer total duration of PN also had a lower gestational age.</p><p><b>CONCLUSIONS</b>Total duration of PN, total amino acid intake, maximum daily amino acid intake, total lipid intake, maximum daily lipid intake, intravenous calorie intake on the 14th day of PN, low birth weight, and neonatal infection and anemia are the risk factors for PNAC. Other risk factors need further investigation.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Ingestión de Energía
/
Recien Nacido Prematuro
/
Grasas de la Dieta
/
Estudios de Casos y Controles
/
Colestasis
/
Estudios Retrospectivos
/
Factores de Riesgo
/
Nutrición Parenteral
/
Aminoácidos
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Factores de riesgo
Límite:
Femenino
/
Humanos
/
Masculino
/
Recién Nacido
Idioma:
Chino
Revista:
Chinese Journal of Contemporary Pediatrics
Año:
2013
Tipo del documento:
Artículo
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