Polymorphisms of (CAG)n and(GGN)n repeats of androgen receptor gene among ethnic Hui and Han Chinese from Ningxia / 中华医学遗传学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To compare the distribution of (CAG)n and (GGN)n repeats polymorphisms of androgen receptor (AR) gene between Hui and Han ethnic Chinese from Ningxia.</p><p><b>METHODS</b>Genotypes of above repeats were determined with DNA sequencing method.</p><p><b>RESULTS</b>The distribution of (GGN)n repeats was significantly different between the two ethnic groups (P< 0.01), though no such difference was detected with (CAG)n repeats (P> 0.05). Particularly, Han Chinese women carrying 23 GGN repeats were significantly fewer (48.4%) than Hui women (64.7%, P=0.01).</p><p><b>CONCLUSION</b>The distribution of GGN repeat is significantly differently among Hui and Han Chinese ethnics from Ningxia.</p>