Aldosterone/plasma renin activity ratio is a sensitive parameter for screening patients with primary aldosteronism / 中华心血管病杂志
Chinese Journal of Cardiology
;
(12): 873-876, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-238500
ABSTRACT
<p><b>OBJECTIVE</b>To screen primary aldosteronism cases with ARR (aldosterone/plasma renin activity, ARR) from patients with hypertension, and to evaluate the diagnosis value of ARR in primary aldosteronism cases and analysis the clinical characters of primary aldosteronism cases.</p><p><b>METHODS</b>Nine hundred and two patients with hypertension were collected, the plasma aldosterone concentration to plasma renin activity ratio were detected by radio-immunity method, after that, ARR were calculated. Retrospective analysis was made of clinical data in 126 primary aldosteronism cases, which ARR were over 25.</p><p><b>RESULTS</b>One hundred and twenty-six cases (14%) were diagnosed as primary aldosteronism, and of them, 49 cases had hypokalemia. 25 patients received surgical operation and the rate of efficiency and cure of surgery treatment were 100% and 48%, respectively. The rate of efficiency and cure of drug treatment was 89% and 24% respectively.</p><p><b>CONCLUSIONS</b>Primary aldosteronism affects over 10% of patients with hypertension in China. Patients with hypertension and most patients with treatment-resistant hypertension should undergo screening for primary aldosteronism with ARR. A high ARR is a positive screening test result, a finding that warrants confirmatory testing.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Potasio
/
Sistema Renina-Angiotensina
/
Sangre
/
Estudios de Seguimiento
/
Renina
/
Pruebas de Química Clínica
/
Diagnóstico
/
Aldosterona
/
Hiperaldosteronismo
/
Hipertensión
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
/
Estudio de tamizaje
Límite:
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Cardiology
Año:
2006
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS