Gap junction and diabetic foot / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 684-688, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-239633
ABSTRACT
Gap junctions play a critical role in electrical synchronization and exchange of small molecules between neighboring cells; connexins are a family of structurally related transmembrane proteins that assemble to form vertebrate gap junctions. Hyperglycemia changes the structure gap junction proteins and their expression, resulting in obstruction of neural regeneration, vascular function and wound healing, and also promoting vascular atherosclerosis. These pathogenic factors would cause diabetic foot ulcers. This article reviews the involvement of connexins in pathogenesis of diabetic foot.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Regeneración
/
Cicatrización de Heridas
/
Uniones Comunicantes
/
Pie Diabético
/
Conexinas
/
Aterosclerosis
/
Hiperglucemia
/
Metabolismo
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Zhejiang University. Medical sciences
Año:
2015
Tipo del documento:
Artículo
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