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Is islet transplantation ready for widespread use in diabetes? / 中华医学杂志(英文版)
Chinese Medical Journal ; (24): 935-938, 2011.
Artículo en Inglés | WPRIM | ID: wpr-239921
ABSTRACT
Up till 2000 when Edmonton group introduced islet transplant procedure in conjunction with a novel glucocorticoid-free immunosuppressive regimen rendering 100% (n=7) of patients with type 1 diabetes insulin-independent for at least 1 year, islet transplant was taken into the clinic. Although significant progress in clinical islet transplant has occurred during recent years, challenges remain, including shortage of available donor organs, technical aspects of islet preparation and transplantation, immunological rejection post-transplant, unclear long-term outcomes of islet transplantation. Special attention is given to current limitation in islet transplantation together with new possible strategies that raise expectations for the widespread use of islet transplantation in the future.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Cirugía General / Trasplante de Islotes Pancreáticos / Usos Terapéuticos / Diabetes Mellitus / Alergia e Inmunología / Inmunosupresores / Métodos Límite: Humanos Idioma: Inglés Revista: Chinese Medical Journal Año: 2011 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Cirugía General / Trasplante de Islotes Pancreáticos / Usos Terapéuticos / Diabetes Mellitus / Alergia e Inmunología / Inmunosupresores / Métodos Límite: Humanos Idioma: Inglés Revista: Chinese Medical Journal Año: 2011 Tipo del documento: Artículo