Clinical analysis of amphotericin B in the treatment of invasive fungal infections in 121 patients with hematologic diseases / 中华血液学杂志
Chinese Journal of Hematology
;
(12): 619-622, 2008.
Artículo
en Chino
| WPRIM
| ID: wpr-239971
ABSTRACT
<p><b>OBJECTIVE</b>To observe the efficacy and safety of amphotericin B for treatment of invasive fungal infections (IFI) in patients with hematologic diseases.</p><p><b>METHODS</b>121 patients were given amphotericin B 5 -50 mg/d for 5 - 101 d with a median of 19 d.</p><p><b>RESULTS</b>The clinical efficacy rate was 67.3%, and fungal elimination rate 66.7%. The adverse events included rigor and fever, hypokalaemia, hepatic damage, nephrotoxicity, nausea and vomiting, phlebitis and teeter.</p><p><b>CONCLUSION</b>Amphotericin B is still a high-efficiency drug in the treatment of IFI, although it has many side effects. With monitoring of hepatic and renal function, it is still a relatively safe and effective drug.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Anfotericina B
/
Resultado del Tratamiento
/
Usos Terapéuticos
/
Quimioterapia
/
Micosis
/
Antifúngicos
Límite:
Adolescente
/
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Hematology
Año:
2008
Tipo del documento:
Artículo
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