The GATA family in reproduction / 中华男科学杂志
National Journal of Andrology
;
(12): 932-936, 2009.
Artículo
en Chino
| WPRIM
| ID: wpr-241227
ABSTRACT
The GATA family proteins are a group of zinc finger transcription factors that are expressed in human and mammalian animals and play an important role in mammalian organ morphogenesis, cell proliferation and sex differentiation. GATA-4 and GATA-6 have been identified in the ovaries and testes of humans, mice, pigs and chickens. GATA-4 contributes to fetal male gonadal development by regulating the genes that mediate Müllerian duct regression and the onset of testosterone production. GATA-4 and GATA-6 are localized in and regulate the function of the ovarian and testicular somatic cells of fetal mice, especially granulosa cells, thecal cells, Sertoli cells and Leydig cells. GATA-4 is also present in the germ cells of fetal and prepubertal mice.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Ovario
/
Reproducción
/
Porcinos
/
Testículo
/
Factores de Transcripción
/
Pollos
/
Embriología
/
Clasificación
/
Factor de Transcripción GATA4
/
Factor de Transcripción GATA6
Tipo de estudio:
Estudio pronóstico
Límite:
Animales
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
National Journal of Andrology
Año:
2009
Tipo del documento:
Artículo
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