Molecular characterization of Vibrio cholerae phage-type 6b epidemic isolates from 1998 to 2001 in Sichuan province / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 409-412, 2009.
Artículo
en Chino
| WPRIM
| ID: wpr-242640
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the molecular characteristics of phage-type 6b isolates emerging in 1998-2001 cholera epidemics in Sichuan province.</p><p><b>METHODS</b>Isolates were analyzed by phage-typing, pulsed field gel electrophoresis (PFGE) and ompW gene sequencing.</p><p><b>RESULTS</b>All phage-type 1b and 6b isolates in Sichuan province from 1998 to 2001 were toxigenic. A total of 24 patterns were identified after PFGE analysis, and one predominant pattern consisted of 13 isolates. Several 1b and 6b isolates from Sichuan and isolates of the 1b from other provinces showed the same PFGE pattern. Mutation in ompW gene was found in 6b isolates.</p><p><b>CONCLUSION</b>V.cholerae O1 6b isolates in Sichuan province from 1998 to 2001 have special genetic markers, and might genetically correlate with contemporaneous 1b isolates.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Vibrio cholerae
/
ADN Bacteriano
/
Tipificación de Bacteriófagos
/
China
/
Cólera
/
Epidemiología
/
Técnicas de Tipificación Bacteriana
/
Clasificación
/
Electroforesis en Gel de Campo Pulsado
/
Genes Bacterianos
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
Chinese Journal of Preventive Medicine
Año:
2009
Tipo del documento:
Artículo
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